Muscimol (also known as agarin or pantherine) is the principal psychoactive constituent of Amanita muscaria and related species of mushroom. Muscimol acts as a potent, selective agonist for the GABAA receptors and displays sedative-hypnotic and dissociative psychoactivity. The psychoactive dose of ...
Noscapine (also known as Narcotine, Nectodon, Nospen, Anarcotine and (archaic) Opiane) is a benzylisoquinoline alkaloid from plants of the Papaveraceae family, without painkilling properties. This agent is primarily used for its antitussive (cough-suppressing) effects. There are anecdotal reports ...
Butane is an organic compound with the formula C4H10 that is an alkane with four carbon atoms. Butane is a gas at room temperature and atmospheric pressure. Inhalation of butane can cause euphoria, drowsiness, narcosis, asphyxia, cardiac arrhythmia, fluctuations in blood pressure, temporary memory ...
Salvia divinorum (also known as Diviner's Sage, Ska María Pastora, Seer's Sage, and by its genus name Salvia) is a psychoactive plant which can induce "visions" and other hallucinatory experiences. Its native habitat is in cloud forest in the isolated Sierra Mazateca of Oaxaca, ...
An entheogen ("generating the divine within")[4] is a chemical substance used in a religious, shamanic, or spiritual context that may be synthesized or obtained from natural species. The chemical induces altered states of consciousness, psychological or physiological (e.g. bullet ...
Ketamine is a drug with multiple applications used in medical procedures with humans and subsequently adopted for veterinary medicine, mainly for starting and maintaining general anesthesia. Other uses include sedation in intensive care, as a pain killer (particularly in emergency medicine and ...
Amantadine (trade name Symmetrel, by Endo Pharmaceuticals) is a drug that has U.S. Food and Drug Administration approval for use both as an antiviral and an antiparkinsonian drug. Rimantadine is a closely related derivative of adamantane with similar biological properties. Rimantadine can produce ...
Cyclizine is an antihistamine drug used to treat nausea, vomiting and dizziness associated with motion sickness, vertigo and post-operatively following administration of general anaesthesia and opioids. Some people using methadone recreationally combine cyclizine with their methadone dose, a ...