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Are abnormal, spherical masses aggregates of protein that develop in the nerve cells. It displaces other cell components and is composed of the protein alpha-synuclein. It is named after the one who discovered it.
Also known as Steele-Richardson-Olszewski syndrome, is a degenerative disease that involves gradual death and deterioration of volumes of the brain. It is named after the Canadian physicians who described it.
A disease or condition with unknown cause or that arises spontaneously. The cause may not be readily apparent or characterized. It is a term from the classification of a disease in nosology.
Also known as hypokinetic rigid syndrome, paralysis agitans, idiopathic or primary parkinsonism, is a progressive, degenerative disorder of the central nervous system. It causes unknown death of dopamine cells in the region of the midbrain.
The process of detecting antigens such as proteins in tissue cells by using antibodies' principle of binding to specific antigen. It is widely used in abnormal cell diagnosis that is found in cancerous cells.
Are extracellular, insoluble fibrous protein aggregates that exhibit beta sheet structure and arises from 18 folded versions of proteins. They form insoluble fibrils which interact with one another. These are amyloid species found in intracellular locations.
The complete or partial muscle wasting of a certain part of the body. It is caused by mutations, poor circulation and nutrition, loss of hormonal support and nerve supply and lack of use of the specific part.
The outermost structure of neural tissue of the cerebrum which covers the cerebrum. It is divided into two cortices and is referred as grey matter because it is composed of cell bodies and capillaries.
