Penicillin is a group of antibiotics derived from Penicillium fungi, including penicillin G (intravenous use), penicillin V (oral use), procaine penicillin, and benzathine penicillin (intramuscular use). Penicillin antibiotics were among the first drugs to be effective against many previously serious diseases, such as bacterial infections caused by staphylococci and streptococci. Penicillins are still widely used today, though misuse has now made many types of bacteria resistant. All penicillins are β-lactam antibiotics and are used in the treatment of bacterial infections caused by susceptible, usually Gram-positive, organisms. Several enhanced penicillin families also exist, effective against additional bacteria: these include the antistaphylococcal penicillins, aminopenicillins and the more-powerful antipseudomonal penicillins.