Home > Term: antibody-directed enzyme pro-drug therapy (ADEPT)
antibody-directed enzyme pro-drug therapy (ADEPT)
A way to target a drug to a specific tissue. The drug is administered as an inactive pro-drug, and then converted into an active drug by an enzyme administered with a second injection. The enzyme is coupled to an antibody that concentrates it in the target tissue. When the enzyme arrives at the target tissue, the pro-drug is activated to form the active drug, while elsewhere it remains inactive.
- Part of Speech: noun
- Industry/Domain: Biotechnology
- Category: Genetic engineering
- Organization: FAO
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- bluemoon
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