Casino Lisboa is one of the most famous hotel casinos in Macau, China. The casino is owned by the Sociedade de Turismo e Diversões de Macau (STDM), a Stanley Ho company. This three-storey complex was built in late 1960s.

The original casino and the 12-storey round hotel tower were built in 1970 by Stanley Ho, Teddy Yip, Yip Hon and Henry Fok. A 270-room extension was added in 1991 for a total of 927 rooms.

In 2006, another extension, the Grand Lisboa, was built next to the current complex. Therefore a total of 2362 rooms are in place in Hotel Lisboa as of 2010. This expansion is being done partly in competition with the newly opened Wynn Macau, located right next to the original Casino Lisboa.