Alice Cullen (born Mary Alice Brandon in 1901) is a precognitive vampire and member of the Olympic coven. She is the wife of Jasper Hale, the adopted daughter of Carlisle and Esme Cullen, the adoptive sister of Emmett Cullen, Edward Cullen and Rosalie Hale. Alice is also the adoptive sister-in-law of Bella Swan and the adoptive aunt of Renesmee Cullen. She also had a younger biological sister, Cynthia Brandon, who remained human and passed away, and a niece, Cynthia's daughter, still living in Biloxi, Mississippi.

In 1920, after having been institutionalized by her family, an unknown vampire turned her to save her from the relentless tracker, James. Later, she was led to the love of her life, Jasper, after receiving a vision of him, and the pair subsequently joined the peaceful coven of the Cullen family. She is known for her sweet and loving nature.