defect in the breaking down or building up of fat below the surface of the skin, resulting in lumps or small dents in the skin surface. (See lipohypertrophy or lipoatrophy.) Lipodystrophy may be caused by repeated injections of insulin in the same spot. - See more at: http://www.diabetes.org/diabetes-basics/common-terms/common-terms-l-r.html#sthash.HEhrY4wn.dpuf